Table 2 TLR2 engagement by DENV is strain specific.

From: TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Virus

Strain

TLR2/NF-κB activation

DENV1

16007

+++

Hawaii

−

DENV2

16681

+++/++a

NGC

+++

TSV01

+

DENV3

16562

+++

H87

−

DENV4

1036

+

H241

−

ZIKV

SL0216

−

WNV

NY99

−

CHIKV

LR OPY1

−

  1. Source data are provided as a source data file.
  2. ++ NF-kB activation is half the triggered by PAM3CSK4, + 10–20% activation of NF-kB in comparison to PAM3CSK4, − Does not trigger NF-kB activation.
  3. aDifferences between various preparations
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