Fig. 1: 3-Dimensional NMR solution structure of arenicin-3.
From: An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria
a Structure displayed in cartoon form showing the classic β-hairpin assembly created by anti-parallel β-sheets and two stabilizing disulfide bonds (yellow) across the sheet, key residues and the N and C terminus labeled for orientation. b Overlay of 20-lowest energy structures, aligned by backbone. c Secondary Hα shifts (variation from random coil). Structure deposited as PDB 5V0Y and BMRB 30259 and images created using PyMol. Structural refinement statistics are displayed in Table 1.
