Fig. 1: Gut microbial alterations in UIA patients.
From: Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms
a Rarefaction curves for gene number in controls (n = 100) and UIA patients (n = 100) after 100 random samplings. b, c Comparison of microbial genus counts and α-diversity (as assessed by the Shannon index) based on the genus profiles in the two groups. Interquartile ranges (IQRs; thick bars), medians (open dots on the bars), the lowest and highest values within 1.5 times IQR from the first and third quartiles (lines above and below the bars). d Principal coordinate analysis of samples from UIAs and controls. e β-diversity (as assessed by the Bray–Curtis distances) based on the genus profiles in the two groups (n = 100). f Relative abundances of the most abundant genera that showed significant differences between UIA patients and controls. For (a), (e), and (f), boxes represent the IQRs between the first and third quartiles, and the line inside the box represents the median; whiskers represent the lowest or highest values within 1.5 times IQR from the first or third quartiles. For (b), (c), and (f), the two-tailed Wilcoxon rank-sum test was used. For (e), ANOSIM analysis was performed. Source data are provided as a Source Data file.
