Fig. 5: Biological Evaluation of 7 inside a mouse model.
From: Rationally designed ruthenium complexes for 1- and 2-photon photodynamic therapy
In vivo PDT study of 7 using 1P (500 nm, 60 min, 10.0 mW cm−2, and 36 J cm−2) or 2P (800 nm, 50 mW, 1 kHz, pulse width 35 fs, and 5 s mm−1) excitation on nude mice bearing a doxorubicin-selected P-gp-overexpressing human colon cancer tumor (SW620/AD300). a Tumor growth inhibition curves upon treatment. b Average body weights of the tumor-bearing mice. c Representative photographs of the tumor-bearing mice. The error bars correspond to the standard deviation of the five replicates.
