Fig. 6: Analysis of the global gut microbiota data in phylum level.
From: Analysis of compositions of microbiomes with bias correction
Data are represented by effect size (log fold change) and 95% confidence interval bars (two-sided; Bonferroni adjusted) derived from the ANCOM-BC model. All effect sizes with adjusted p < 0.05 are indicated, *significant at 5% level of significance; **significant at 1% level of significance; ***significant at 0.1% level of significance. Exact adjusted p values can be found in Supplementary Table 1. Diamonds on top of some bars indicate structural zeros. a Pairwise differential abundance analyses stratified by age using ANCOM-BC: Infants (age ≤ 2 years, n = 133), and adults (18 ≤ age ≤ 40, n = 83). Infant samples are colored in red and adult samples are colored in green. Phyla Acidobacteria and Chloroflexi are not represented in the plot since they are present only in Venezuela samples. b Pairwise tests using ANCOM-BC for the equality of mean log ratio of Bacteroidetes to Firmicutes stratified by age. Viewing b and Supplementary Table 2 together, lower BMI seems to be associated with higher levels of the Bacteroidetes to Firmicutes ratio, a result widely acknowledged in the literature.
