Fig. 2: Increased expression of activation markers on T cells in SARS-CoV-2 infected patients.
From: Immunological and inflammatory profiles in mild and severe cases of COVID-19
a Representative dot plots showing CD38 and HLA-DR expression on CD8+ and CD4+ T cells from PBMCs of HC, Mild and Severe COVID-19 patients. b, c The percentage of CD38 and HLA-DR single positive or double positive b CD8+ T cells or c CD4+ T cells in PBMCs of HC (n = 6), mild (n = 29) and severe (n = 12) SARS-COV-2 infected patients was assessed by flow cytometry. Colored symbols indicated deceased cases. Data are expressed as mean ± SD. *p < 0.05, ***p < 0.001, ****p < 0.0001, by two-tailed Mann–Whitney U-test for b (p < 0.0001 and p = 0.0001 for CD38+CD8+T cells, p = 0.0135 for HLA-DR+CD8+T cells, and p = 0.0002, p = 0.0001, and p = 0.0372 for HLA-DR+CD38+CD8+T cells) and c (p = 0.0088 and p = 0.0046 for HLA-DR+CD38+CD4+T cells, respectively). Source data included as a Source Data File.
