Fig. 1: Overall structure of the DOCK2−ELMO1−RAC1 complex.
From: Structure of the DOCK2−ELMO1 complex provides insights into regulation of the auto-inhibited state

a Schematic of the domain structures of DOCK2, ELMO1 and RAC1. b, c Two views of the cryo-EM map of the DOCK2−ELMO1−RAC1 complex with each domain colour-coded. Ribbon representation of the structural models were placed in the cryo-EM density map. The two DOCK2−ELMO1−RAC1 protomers of the dimeric complex are indicated by light blue and light yellow backgrounds. The open-conformation of the DOCK2−ELMO1−RAC1 complex is shown.