Fig. 5: Safe design of WS2 and MoS2 by surface passivation.
From: Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
a Schematic images to passivate nanosheet surfaces. b Assessment of surface passivation by hemolysis or abiotic DCF assay (n = 3 independent experiments). Data are presented as mean values ± SD. c Representative images of lysosomal release of Fe2+ and d cell viability test in cells exposed to modified TMDs. To assess the impacts of surface passivation, BEAS-2B and THP-1 cells were exposed to 200 μg/mL nanosheets for 48 h. The treated cells were subject to MTS assay or FeRhoNox staining for confocal imaging (n = 3 biologically independent cell samples). Scale bar represents 10 μm. Cell viability data are presented as mean values ± SD. *p < 0.05, **p < 0.01 compared to the pristine TMD-treated cells by two-tailored Student t-test.
