Table 3 Univariable and multivariable analysis of factors associated with having detectable antibodies (IgM and/or IgG and/or IgA).

From: Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

     

Univariable analysis

Multivariable analysis

  

Negative (n = 524)

Positive (n = 54)

P value

OR

(95% CI)

p value

OR

(95% CI)

p value

Sexa

Male

148 (28%)

13 (24%)

0.52b

1

 

0.52

   

Female

376 (72%)

41 (76%)

 

1.24

(0.65; 2.38)

    

Agec,d

 

42 (12)

40 (12)

0.11e

0.98

(0.96; 1.00)

0.11

0.98

(0.95; 1.00)

0.09f

Professional categorya

Otherg

90 (17%)

8 (15%)

0.89b

1

 

0.89

   

Lab technician/other tech.

41 (8%)

4 (7%)

1.10

(0.31; 3.85)

   

Nurses/auxiliary nursesi

262 (50%)

26 (48%)

1.12

(0.49; 2.55)

   

Physicians

131 (25%)

16 (30%)

1.37

(0.56; 3.35)

   

Daily contact with patientsa

No

113 (22%)

10 (19%)

0.60b

1

 

0.60

   

Yes

411 (78%)

44 (81%)

 

1.21

(0.59; 2.48)

    

Working in a COVID-19 unita

No

284 (54%)

31 (57%)

0.65b

1

 

0.65

   

Yes

240 (46%)

23 (43%)

 

0.88

(0.50; 1.55)

    

Close contact with COVID-19 confirmed or suspected casea

No

127 (24%)

10 (19%)

0.35b

1

 

0.35

   

Yes

397 (76%)

44 (81%)

1.41

(0.69; 2.88)

   

Previously diagnosed with COVID-19 by rRT-PCRa

No

518 (99%)

21 (39%)

<0.0001j

1

 

<0.0001

   

Yes

6 (1%)

33 (61%)

135.67

(51.27; 359.01)

   

Comorbiditiesa,h

No

471 (90%)

46 (85%)

0.28b

1

 

0.29

   

Yes

53 (10%)

8 (15%)

 

1.55

(0.69; 3.45)

   

Household sizec,d

 

2.7 (1.2)

2.9 (1.1)

0.37e

1.11

(0.88; 1.41)

0.37

1.25

(0.96; 1.62)

0.09f

Received Flu vaccine (2019–2020 season)a

No

309 (59%)

30 (56%)

0.63b

1

 

0.63

   

Yes

215 (41%)

24 (44%)

 

1.15

(0.65; 2.02)

   

Reporting COVID-19 compatible symptom within the previous monthsa

No

357 (68%)

11 (20%)

<0.0001b

1

 

<0.0001

1

 

<0.0001f

Yes

167 (32%)

43 (80%)

8.36

(4.20; 16.61)

8.84

(4.41; 17.73)

  1. an (Column percentage).
  2. bChi-squared test.
  3. cArithmetic mean (SD) [n].
  4. dOdds ratio per unit increase.
  5. eT-test.
  6. fWald test.
  7. gIncludes, cleaning, kitchen and maintenance staff.
  8. hComorbidities include: heart and liver disease, diabetes, chronic respiratory and renal disease, cancers and autoimmune, and other immunological disorders.
  9. iIncludes strecher-bearer.
  10. jFisher’s exact test.
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