Table 1 Equal replication rates of genome-wide significant loci by MOSTest and min-P.

From: Understanding the genetic determinants of the brain with MOSTest

Test

Feature set

# loci discovered

# loci replicated

Fraction replicated

MOSTest

All

347

122

0.35

MOSTest

Subcortical

177

68

0.38

MOSTest

Surface area

139

58

0.42

MOSTest

Cortical thickness

71

24

0.34

min-P

All

115

48

0.42

min-P

Subcortical

90

40

0.44

min-P

Surface area

53

24

0.45

min-P

Cortical thickness

24

9

0.38

  1. Results from the replication of the genome-wide significant loci are identified through MOSTest and min-P in an additional sample of 4884 individuals. The column “# loci replicated” indicates the amount of discovered loci in the main analysis that surpass a nominal significance (p = 0.05) in the replication sample. The “fraction replicated” column divides the number of loci discovered in the main analysis with the number of loci that replicated.
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