Fig. 5: sigLASSO is computationally efficient. | Nature Communications

Fig. 5: sigLASSO is computationally efficient.

From: Using sigLASSO to optimize cancer mutation signatures jointly with sampling likelihood

Fig. 5

a Running time of sigLASSO and deconstructSigs at different total mutations numbers. Box edges are the 25th and 75th percentiles and whiskers indicate the 1.5× IQR or max/min, which ones are smaller. b Running time of sigLASSO at different numbers of signatures (downsampled from 30 COSMIC signatures) simulated with three different mutations numbers (in parenthesis). Noise level: 0.1 sL: sigLASSO, dS: deconstructSigs.

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