Fig. 2: Genome assembly and architecture.
a Hi-C contact map, visualised in Juicebox.js, with number of contacts coloured in blue according to the scale below. b Histogram of assembly scaffold sizes and corresponding chromosomes drawn to scale after Ishijima et al.29 Note the large difference in size between chromosome 1 and the additional 22 chromosomes, which was reflected in our assembly. c Representation of the relative completeness of the E. muelleri assembly compared to those of a number of commonly used genomes. N50 is represented by diameter of circles and number of scaffolds / genome size are on the x and y axes, respectively. The high level of contiguity of our assembly is obvious in this comparison. d Conserved syntenic signal in Ephydatia muelleri with Trichoplax adhaerens, e and with Branchiostoma floridae. Each small green dot on the matrices represents an identified homologous gene pair. Individual scaffolds for each species pair possess numerous homologous genes. Red-boxed locations are shown in detail to the right of each matrix as chromosomal representations. Each black line on the chromosome images represents a gene linked in green to the homologous gene in the other species. It is clear that numerous genes are conserved between ancestrally homologous chromosomal regions between these species, although their relative arrangement within chromosomes is shuffled, as expected under the DCJ-DS model of syntenic evolution. Source data are provided as a Source Data file.
