Fig. 3: Tumor phylogenies.
From: Accelerated single cell seeding in relapsed multiple myeloma
Phylogenetic trees generated from the Dirichlet process analysis were drawn such that the trunk and branch lengths were proportional to the (sub)clone mutational load, a I-H-106917, b I-H-130718, c I-H-130719 and d I-H- 130720. All main drivers (CNA, copy number aberrations; SNV, single nucleotide variants and SV, structural variants) were annotated according to their chronological occurrence and colored according to the type of event. Known driver SNVs were annotated in green, single SVs and CNAs in black (HRD = hyperdiploid), translocations associated with copy number changes in dark red, chromothripsis in blue, other complex events in dark yellow, (TI = templated insertion). Lines from different subclone branches are separated by hooks. Patients with short survival are positioned on the right (I-H-130718 and I-H-130720). L = left.
