Fig. 3: Interface of the nsp10-nsp16 protein complex.

a Surface representation of the nsp10-nsp16 protein complex where the interface is labeled in blue (nsp10) and yellow (nsp16). b Bottom view of the nsp10 interface; box provides better detail. The interface residues of nsp10 are depicted in blue stick representation. c Top view of the nsp16 interface in yellow, where all interface residues are depicted in yellow and shown in greater detail in the box. d Side view of the nsp10-nsp16 interface, further details are shown in Supplementary Fig. 2. e Residue Leu45 immersed into the hydrophobic pocket defined by interface residues Pro37, Ile40, Val44, Ala45, Thr48,Val84, Leu244, and Met247 of nsp16 (illustrated in partially transparent interface representation in yellow). Involvement of solvent molecules is shown in Supplementary Fig. 2.