Fig. 4: Sinefungin recognition by the nsp16 MTase.

a SARS-CoV-2 nsp10-nsp16 protein complex bound to sinefungin (white sticks), nsp16 in surface representation (cyan), nsp10 in cartoon representation (orange), and zinc ions as gray spheres. b Detailed view of sinefungin recognition, important amino acid residues are shown in stick representation, waters as red spheres, and hydrogen bonds are shown as dashed lines.