Fig. 1: Hierarchical self-assembling synthesis of MOF-gated MS nanoadjuvants. | Nature Communications

Fig. 1: Hierarchical self-assembling synthesis of MOF-gated MS nanoadjuvants.

From: A nanoscale metal organic frameworks-based vaccine synergises with PD-1 blockade to potentiate anti-tumour immunity

Fig. 1

a Scheme of MS and MOF-gated MS nanostructure, b SEM and TEM images of MS and MOF-gated MS with different ratio of MS/MOF (0.166 M MS, 0.069 M Zn2+; 0.166 M MS, 0.207 M Zn2+; and 0.166 M MS, 0.414 M Zn2+). Scale bars, 200 nm (upper, SEM); 100 nm (down, TEM). c XRD patterns of MS, MOF-gated MS and MOF. d Particle size distribution of MOF-gated MS with different ratio of MS/MOF (0.166 M MS, 0.069 M Zn2+; 0.166 M MS, 0.207 M Zn2+; and 0.166 M MS, 0.414 M Zn2+). e SEM image and f STEM mapping of MOF-gated MS (synthesis parameter: 0.1 M MS, 0.276 M Zn2+). Scale bar in e, 100 nm. Scale bar in f, 50 nm.

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