Table 4 Characteristics of women in Malaysian Breast Cancer Genetic Study and Singapore Breast Cancer Cohort.
Chinese Cases | Chinese Controls | Malay Cases | Malay Controls | Indian Cases | Indian Controls | |
N | ||||||
Overall BC | 5236 | 5156 | 1084 | 1332 | 580 | 1018 |
ER-positive | 3627 | 5156 | 715 | 1332 | 374 | 1018 |
ER-negative | 1365 | 5156 | 336 | 1332 | 184 | 1018 |
Age, years, mean (SD) | 53.1 (10.93) | 51.8 (9.73) | 49.7 (10.18) | 51.1 (8.73) | 53.2 (10.53) | 54.1 (8.75) |
Polygenic risk score, mean (SD) | ||||||
PRSoverall | 0.91 (0.54) | 0.69 (0.54) | 0.85 (0.58) | 0.63 (0.58) | 0.56 (0.57) | 0.33 (0.61) |
PRSER+ | 0.89 (0.57) | 0.63 (0.58) | 0.84 (0.59) | 0.57 (0.62) | 0.55 (0.57) | 0.26 (0.65) |
PRSER− | 1.24 (0.53) | 1.07 (0.52) | 1.11 (0.55) | 0.98 (0.55) | 0.92 (0.57) | 0.75 (0.55) |
