Fig. 6: HF-OCT volumetric microscopy of an intracranial stent partially overlapping with the distal end of a flow diverting stent.

a Three-dimensional rendering showing significant thrombus accumulation. b HF-OCT microscopy depicts the vessel wall microstructure including the individual vessel layers comprising a bright tunica intima, a low-scattering tunica media, and the tunica adventitia (arrows). The internal elastic lamina (IEL) and the external elastic lamina (EEL) are indicated by the green arrows. c A thrombus dislodged from the surface of the device floating inside a large branch is visible and denoted by the asterisk. d Thrombus formations ranging between 100 and 200 µm in thickness are indicated by the asterisks and distributed over the FDS surface. e A semi-occlusive clot formation in correspondence of a significant malapposition (>500 µm) is visible over the proximal end of the FDS. HF-OCT imaging was repeated in a total of n = 15 swine internal maxillary arteries with an intracranial stent partially overlapping with a flow-diverting stent. Scale bars are equal to 1.0 mm. Three-dimensional endoscopic rendering color scheme: red, artery wall; purple, clot; silver, flow-diverting stent struts; gray, neurovascular stent struts.