Table 1 Clinical and demographic characteristics of individuals carrying the reference vs. alternate alleles of KIF3A SNPs rs11740584 and rs2299007.

From: Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk

Clinical variables

rs11740584 Referencea (C)

rs11740584 Alternateb (G)

rs2299007 Referencea (A)

rs2299007 Alternateb (G)

N

27

29

38

18

Black

4 (15%)

10 (34%)

12 (32%)

2 (11%)

Male

18 (67%)

19 (66%)

24 (63%)

13 (72%)

Age

15.7 ± 4.2

14.7 ± 3.4

15.3 ± 3.7

15.1 ± 4.1

History of AD

13 (48%)

15 (52%)

18 (47%)

10 (56%)

TEWLc

1.03 (0.87–1.54)

1.09 (0.85–1.42)

1.02 (0.86–1.44)

1.14 (0.80–1.56)

  1. aReference allele carriers were homozygous for the reference alleles.
  2. bAlternate allele carriers were either heterozygous or homozygous for the alternate alleles.
  3. cTEWL measurements were corrected for day-to-day variation by normalization to the same control subject whose TEWL was measured within 30 min of every subject.
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