Fig. 3: Gonococcal mtrC, mtrA, and farA LOF mutations are associated with cervical infection. | Nature Communications

Fig. 3: Gonococcal mtrC, mtrA, and farA LOF mutations are associated with cervical infection.

From: Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae

Fig. 3: Gonococcal mtrC, mtrA, and farA LOF mutations are associated with cervical infection.The alternative text for this image may have been generated using AI.

a Sexual behavior of patients infected with isolates with either intact or LOF alleles of mtrC (left), mtrA (middle), or farA (right). b Site of infection in patients infected with isolates with either intact or LOF alleles of mtrC (left), mtrA (middle), or farA (right). mtrA alleles were predicted as LOF only in the absence of other epistatic Mtr overexpression mutations. Statistical significance between genotype and patient metadata was assessed by two-sided Fisher’s exact test: *p < 0.05, **p < 0.01, and ***p < 0.001. Exact p-values from left to right for analyses in a were 0.04021, 1.81 × 10−11, 5.06 × 10−10 and for b were 6.49 × 10−5, 1.64 × 10−12, 1.78 × 10−12. WSM = women who have sex with men, MSW = men who have sex with women, MSMW = men who have sex with men and women, MSM = men who have sex with men.

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