Fig. 4: mtrC LOF mutations are enriched in a lineage of ST-11 urogenitally-adapted N. meningitidis.

A core-genome maximum likelihood phylogeny based on 25045 SNPs was estimated of all North American ST-11 N. meningitidis strains from PubMLST (n = 456; accessed 2019–09–03) rooted with meningococcal reference genome MC58. Membership in the ST-11 urogenital clade (dark blue) is defined as in Retchless et al.44. Genomes with mtrC LOF mutations are indicated in pink. Branch length represents substitutions per site.