Fig. 4: Conformation and immunological activities.
From: Chemical synthesis of glycans up to a 128-mer relevant to the O-antigen of Bacteroides vulgatus
a A representative solution conformation of the 32-mer as determined by NMR and molecular simulation (Maestro Schrödinger), prepared with SweetUnitMol39; b ELISA analysis of the competition binding of the glycans and LPS from B. vulgatus to the human C-type lectin DC-SIGN, with LPS from Shigella flexneri as a negative control. The competition experiments have been performed three times showing similar results; the graph shows data of one of these experiments40. Source data are provided as a Source Data file.
