Fig. 4: Lactate production by Lp is necessary and sufficient to reduce yeast appetite in the presence of Ap.
a, b Number of sips on yeast of either germ-free flies (empty boxes) kept in complete holidic medium (grey border boxes), or medium without Ile (-Ile, blue border boxes), or of flies that were monoassociated (light blue) with Ap, or biassociated (dark blue) with both Ap and Lp, or grown in medium containing lactate (burgundy). Filled black circles represent a complete holidic medium, or association with either Ap, wt or mutant Lp, or the presence of lactate in the medium. In a wt denotes the parental LpWCFS1 strain and ∆ldh the deletion mutant LpWCFS1∆ldh. Open black circles represent the absence of specific bacteria or lactate. Boxes represent median with upper and lower quartiles. n represents the number of flies assayed per condition. Significance was tested using a Kruskal–Wallis test with Dunn’s multiple comparison test. Source data are provided as a Source Data file.
