Fig. 2: ER tubules mark the initiation sites of MDT. | Nature Communications

Fig. 2: ER tubules mark the initiation sites of MDT.

From: ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation

Fig. 2

a, b Examples of MDT at ER–mitochondria contacts. Left-hand images show Cos-7 cells expressing a mEmerald-Sec61β and mito-DsRed, and b mCherry-KDEL and Tom20-GFP, merged as indicated. Right graphs are linescans drawn through the mitochondria (dashed box), and show the relative fluorescence intensity of mitochondria (green) and ER (purple) along their lengths. White arrowheads at constrictions in the images correspond to the black arrows shown on the corresponding linescan graphs. Scale bars: 2 μm. Additional examples are shown in Supplementary Fig. 5a–d.

Back to article page