Fig. 1: Recording of putative GCs and MCs.
From: Place cell maps slowly develop via competitive learning and conjunctive coding in the dentate gyrus
a Left, 3D representation of the mouse brain (Allen Mouse Brain Institute; www.alleninstitute.org) showing recording electrode configuration in the dentate gyrus (light green). Dark green, cornus ammonis (CA). Right, the electrode positions (ellipsoid) relative to the lateral/medial edges of the granule cell layer (dashed lines) for all mice. b Left, scheme showing the location of the hilus and granule cell layer on a coronal section of the hippocampus. Right, layout of recording sites for a shank of the silicon probe and profile of local field potential dentate spike 2 (LFP DS2). Red arrow, position of DS2 reversal. c 3D scatter plot for cells’ spike gamma phase, ACG refractory gap and gamma coupling index. Putative MCs (orange dots) and GCs (light blue dots) are identified by overlap with DRD2 (red filled circle) and POMC (blue circle) light-excited cells. d Spike ACGs (upper, color-coded representation of individual cell; lower, population average) for putative GCs (blue), MCs (red) and inhibitory cells (green). e Layout of LFP DS2 (upper) and putative GCs and MCs (lower) along the silicon probe shanks for one session. f Top, distribution of depth differences for all possible pairs of putative GCs and MCs recorded concurrently on the same shanks (n = 825 pairs). Bottom, same analysis between GCs and the population of unclassified cells in panel (c) (n = 301 pairs). Arrows, the means. P-values, two-tailed paired t test.
