Fig. 6: RNA chromogenic in situ hybridization (CISH) for ciRS-7 in various adenocarcinomas.

a–f The adenocarcinomas are derived from a tissue microarray and are originating from cervix (a), lung (b), breast (c), ovarium (d), pancreas (e), and stomach (f). For each cancer type at least two cores containing both cancer cells and tumor stroma were analyzed and showed similar results. The ciRS-7 signal (red dots) is observed in the tumor stroma whereas the cancer cells are negative. Scale bars, corresponding to 100 µm, are indicated in the lower-left corners.