Fig. 5: Model illustrating Cas9 activity during the development of embryos performed by traditional zygote injection methods in the upper panel and Past-CRISPR in the lower panel. | Nature Communications

Fig. 5: Model illustrating Cas9 activity during the development of embryos performed by traditional zygote injection methods in the upper panel and Past-CRISPR in the lower panel.

From: Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation

Fig. 5

Solid scissors represent sufficient amounts of Cas9 with targeting activity, and dashed scissors represent low amounts of Cas9 with weak or no targeting activity. Different colors of different blastomeres represent different mutation genotypes.

Back to article page