Table 2 Parameters of drug loading using BAQ13 NPs.

From: Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy

Drugs or dyes

NPs : drug (mass ratio)

Drug-loading content

Encapsulation efficiency

Size/diameter

PDI

DiD (dye)

1 : 1

50%

100%

120 nm

0.1

Bortezomib

1 : 1

50%

89%

92 nm

0.09

β-lapachone

2 : 1

33%

95%

128 nm

0.047

JQ1

1 : 1

50%

92%

110 nm

0.048

Rapamycin

1 : 1

50%

90%

85 nm

0.15

Etoposide

1 : 1

50%

86%

69 nm

0.104

Apoptozole

1 : 1

50%

93%

85 nm

0.099

Vinblastine

1 : 1

50%

95%

60 nm

0.133

Lenalidomide

1 : 1

50%

88%

85 nm

0.069

Napabucasin

4 : 1

20%

85%

110 nm

0.101