Fig. 1: VX-765 and VRT-043198 are detected in mice after a single dose of VX-765. | Nature Communications

Fig. 1: VX-765 and VRT-043198 are detected in mice after a single dose of VX-765.

From: Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging

Fig. 1: VX-765 and VRT-043198 are detected in mice after a single dose of VX-765.The alternative text for this image may have been generated using AI.

a–c PK measures of VX-765 and active VRT-043198 metabolite in a plasma, b whole brain homogenates, and c CSF samples up to 24 h after a single IP injection of 50 mg · kg−1 VX-765 (n = 2 mice per time point).

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