Table 2 Correlation coefficients (r2) and p values for frailty items with chronological age.
From: Age and life expectancy clocks based on machine learning analysis of mouse frailty
Item | r2 | p value |
|---|---|---|
Tail stiffening | 0.58 | <0.001 |
Breathing rate/depth | 0.50 | <0.001 |
Gait disorders | 0.42 | <0.001 |
Hearing loss | 0.38 | <0.001 |
Kyphosis | 0.38 | <0.001 |
Tremor | 0.38 | <0.001 |
Body condition score | 0.26 | <0.001 |
Forelimb grip strength | 0.20 | <0.001 |
% twc | 0.12 | <0.001 |
Menace reflex | 0.11 | <0.001 |
Alopecia | 0.10 | <0.001 |
Tumors | 0.08 | <0.001 |
Diarrhea | 0.05 | <0.001 |
Penile prolapse | 0.05 | <0.001 |
Microphthalmia | 0.05 | <0.001 |
Dermatitis | 0.05 | <0.001 |
Rectal prolapse | 0.04 | <0.001 |
Distended abdomen | 0.04 | <0.001 |
Eye discharge/swelling | 0.04 | <0.001 |
Coat condition | 0.04 | <0.001 |
Body weight score | 0.02 | 0.01 |
Threshold % rwc | 0.01 | 0.05 |
Loss of fur color | 0.01 | 0.06 |
Piloerection | 0.01 | 0.07 |
Mouse grimace scale | 0.01 | 0.08 |
Vestibular disturbance | 0.01 | 0.16 |
Vision loss | 0.00 | 0.30 |
Loss of whiskers | 0.00 | 0.33 |
% rwc | 0.00 | 0.49 |
Cataracts | 0.00 | 0.68 |
Corneal capacity | 0.00 | 0.72 |
Nasal discharge | 0.00 | 1.00 |
