Fig. 2: Force dependence of length for supercoiled DNA demonstrated by FMT.
From: Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision
a Changes in length are displayed for positive and negative supercoiling states at four flow rates. Negatively supercoiled DNA only compacts at the lowest flow rate, which corresponds to a force below 1 pN. The height of the magnets is held constant. b The mean length as a function of turns and force for a single molecule displays an asymmetric character, where positive buckling is less sensitive to increases in flowrate than negative buckling.
