Fig. 6: The functions of HDAC1/2 and SATB2 in UPRmt activation are conserved in mammals.
From: Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity
a qRT-PCR measures mRNA levels of LONP1 and HSPA9 in HEK293T cells cultured under indicated conditions. b Representative fluorescence images of HeLa cells cultured under the indicated conditions. Scale bar, 10 µm. c qRT-PCR measures mRNA levels of UPRmt genes in HEK293T cells cultured under the indicated conditions. (a, c) n = 3 independent experiments. Results in (a, c) are shown as mean + SD. P values were calculated by two-way ANOVA and Tukey’s multiple comparisons test (**P < 0.01; ***P < 0.001). Source data are provided as a Source Data file.
