Fig. 2: Subsets of macrophages in the melanoma tumors.
From: A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response

The scRNA-seq dataset - GSE120575 was used in this analysis. a Heatmap of z-scored expression of the top up-regulated genes of each macrophage subpopulation versus the other two macrophage subpopulations. b Violin plots of log-transformed gene expression of selected genes showing statistically significant upregulation in inflammatory macrophages (top), TREM2hi macrophages (center), and Immunoregulatory related macrophages (bottom).