Fig. 1: Islet eQTLs and their activity in other tissues.
From: Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
a Proportion of islet eQTLs active in GTEx tissues using p-value enrichment analysis (π1 estimate for replication). b Comparison between eQTLs discovered in islets and their p-values in β-cells (top figure, N = 26) and whole pancreas tissue from GTEX (bottom figure, n = 149). The axes show the −log10 p-value of the eQTL associations adjusted by the eQTL direction (positive or negative) of effect with respect to the reference allele. Source data are provided as a Source data file.
