Fig. 2: Fabp7 is a specific marker for SGC. | Nature Communications

Fig. 2: Fabp7 is a specific marker for SGC.

From: Satellite glial cells promote regenerative growth in sensory neurons

Fig. 2

a Representative images of immunofluorescence staining of mouse DRG sections with FABP7 (green) which labels SGC surrounding neurons marked with TUJ1 (magenta). No FABP7 expression in the axon rich area (asterisks) is observed. n = 3 biologically independent animals, Scale bar: 100 µm. b BLBPCre-ER mice crossed with RosaGFP or Sun1GFP show expression of GFP in the SGC surrounding the neurons marked with TUJ1 (magenta). RosaGFP n = 3 and Sun1GFP n = 4 biologically independent animals, Scale bar: 50 µm. c Quantification of sciatic nerves from BLBPCre-ER mice crossed with Sun1GFP. GFP positive nuclei were normalized to the total number of DAPI positive nuclei. One-way analysis of variance (ANOVA) followed by Sidak’s multiple comparisons test. Data are presented as mean values ± SEM. Source data are provided as a Source Data file. d Representative images from naive and injured nerves, ~0.5 mm proximal and distal to the injury site as shown in the scheme. n = 4 biologically independent animals. Scale bar: 50 µm.

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