Table 1 Clinical characteristics of secondary M. tuberculosis cases from each TB pair according to time of reactivation.

From: Mycobacterium tuberculosis progresses through two phases of latent infection in humans

Variablea

Early reactivation (0–2 yrs)

Late reactivation (>2 yrs)

p valueb

Age (years)

23.4 (n = 11)

29.5 (n = 13)

0.35

Gender

  

0.41

  Male

7

5

 

  Female

4

8

 

 Body mass index

19.9 (n = 6)

21.0 (n = 11)

0.42

BCG vaccine scar

  

1.0

  Yes

10

10

 

  No

1

2

 

  NA

0

1

 

HIV status (self- reported):

  

1.0

  HIV Positive

0

0

 

  HIV Negative

6

12

 

  NA

5

2

 

 PPD max (mm)

12.9 (n = 10)

14.7 (n = 8)

0.56

Alcohol use

  

1.0

  Yes

1

1

 

  No

4

5

 

  NA

6

8

 

Smoking

  

1.0

  Yes

1

1

 

  No

4

5

 

  NA

6

8

 

Comorbiditiesc

  

0.47

  Yes

0

2

 

  No

5

5

 

  NA

6

7

 
  1. aMeans are shown for numerical variables (age, body mass index, and PPD max), frequencies are shown for categorical variables (gender, BCG vaccine scar, HIV status, alcohol use, smoking, and co-morbidities). Not all data was available for each patient. Each variable value is indicated by the sample size used to derive the value.
  2. bp Values comparing clinical characteristics in early vs. late reactivation are estimated using exact tests for categorical values (using available data only) and Wilcoxon rank sum tests for numerical variables.
  3. cComorbidities include: renal failure, diabetes, cancer, rheumatoid arthritis, COPD or gastric surgery.
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