Table 1 Gene expression profiling of MNCs in the presence or absence of PMP treatment.

From: Platelet-derived microparticles enhance megakaryocyte differentiation and platelet generation via miR-1915-3p

Molecular and cellular function

Fold enrichment

P-value

Number of molecules

FDR

Blood coagulation

1.739779

1.24E−09

184/486

4.80E−06

Innate immune response

1.538794

1.30E−08

257/770

2.51E−05

Immune response

1.834004

2.47E−08

130/324

3.18E−05

Inflammatory response

1.811905

3.40E−08

132/333

3.28E−05

Platelet activation

1.966704

2.15E−07

92/213

0.000166

Signal transduction

1.419512

4.08E−07

300/974

0.000263

Cytokine-mediated signaling pathway

1.797146

1.24E−06

103/261

0.000685

Type I interferon signaling pathway

2.691139

1.74E−06

41/69

0.000843

Adaptive immune response

2.064937

6.37E−06

61/134

0.002737

Response to lipopolysaccharide

1.979213

9.54E−06

65/149

0.003686

  1. The functional summary of the differentially expressed mRNAs (>1.2-fold or <0.833-fold changes) is shown. The PANTHER Classification System (http://pantherdb.org/) was used for Gene Ontology analysis.
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