Fig. 2: Co-infections in COVID-19 lungs identified by WGS metagenomics.
From: Two distinct immunopathological profiles in autopsy lungs of COVID-19
No differences in co-infections in ISGhigh and ISGlow COVID-19 lungs identified by WGS metagenomics. a Total number of reads generated for each sample. b Percentage of reads and c absolute numbers of reads not mapping to the human genome (GRCh37 hg19) (n = 34 independent samples). Box-plots elements indicate the median (center line), upper and lower quartiles (box limits). Whiskers extend to the most extreme value included in 1.5× interquartile range. d Bacterial and e viral co-infections across lung samples, WGS metagenomic analysis. Purple dots, numbers of reads sufficient for identification of non-human species. Samples are ordered by increasing the SARS-CoV-2 viral load in both the ISGlow and the ISGhigh group. Stacked bars, the relative abundance of the most common species. Gray bars represent frequent species, colored bars show pathogenic species. *One COVID-19 patient (C3) clustered in the normal control group. ISGhigh samples, red; ISGlow samples, blue.
