Fig. 4: Immune cell infiltrates on COVID-19 lung sections.

a Frequencies of immune cells on ISG^high and ISG^low COVID-19 lung sections and controls (n = 33 for CD4 and CD20, n = 31 for CD123, n = 32 for CD8/PD1). Box-plots elements indicate the median (center line), upper and lower quartiles (box limits). Whiskers extend to the most extreme value included in 1.5× interquartile range. Groups were compared using a two-sided Wilcoxon rank-sum test. b Representative immunohistochemistry (CD4, CD20, CD123, CD8/PD1) of ISG^high and ISG^low COVID-19 lungs and controls, size bar 500 μm. At least two different tissue blocks from different areas of the lungs were evaluated for each case. ISG^high samples, red; ISG^low samples, blue.