Table 2 Gene ontology enrichment analysis of genes upregulated in COVID-19 samples.
From: Two distinct immunopathological profiles in autopsy lungs of COVID-19
ID | Description | GeneRatio | BgRatio | p-value | p.adjust |
|---|---|---|---|---|---|
GO:0034340 | Response to type I interferon | 17/66 | 30/379 | 3.70E−07 | 0.000158 |
GO:0060337 | Type I interferon signaling pathway | 17/66 | 30/379 | 3.70E−07 | 0.000158 |
GO:0071357 | Cellular response to type I interferon | 17/66 | 30/379 | 3.70E−07 | 0.000158 |
GO:0051607 | Defense response to virus | 21/66 | 44/379 | 5.53E−07 | 0.000177 |
GO:0098542 | Defense response to other organism | 25/66 | 71/379 | 3.85E−05 | 0.009888 |
GO:0009615 | Response to virus | 21/66 | 57/379 | 9.79E−05 | 0.020960 |
GO:0045069 | Regulation of viral genome replication | 10/66 | 18/379 | 1.87E−04 | 0.034381 |
GO:1903900 | Regulation of viral life cycle | 11/66 | 22/379 | 2.95E−04 | 0.042931 |
GO:0045071 | Negative regulation of viral genome replication | 8/66 | 13/379 | 3.57E−04 | 0.042931 |
GO:1903901 | Negative regulation of viral life cycle | 8/66 | 13/379 | 3.57E−04 | 0.042931 |
GO:0048525 | Negative regulation of viral process | 9/66 | 16/379 | 3.68E−04 | 0.042931 |
GO:0051603 | Proteolysis involved in cellular protein catabolic process | 7/66 | 11/379 | 6.71E−04 | 0.071789 |
GO:0050792 | Regulation of viral process | 12/66 | 28/379 | 9.17E−04 | 0.088399 |
GO:0019079 | Viral genome replication | 10/66 | 21/379 | 9.64E−04 | 0.088399 |
GO:0043901 | Negative regulation of multi-organism process | 9/66 | 18/379 | 1.16E−03 | 0.099123 |
