Fig. 3: ATPTT2 anchors IF1 to the membrane. | Nature Communications

Fig. 3: ATPTT2 anchors IF1 to the membrane.

From: Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization

Fig. 3

a ATPTT2 interacts with the IF1 C-terminal domains, which dimerizes via their helical hairpins. Close-up view shows the interaction interface between ATPTT2 and IF1 C-terminal dimer. b IF1 C-terminal interact via electrostatic interactions on the periphery, and c form a tight hydrophobic core. d Type III ATP synthase dimer with bound intra-dimeric IF1. The elements forming C-terminal dimer, interact with ATPTT2 and F1 are indicated in right panel. e porcine type I ATP synthase tetramer (PDB 6J5K) [https://www.rcsb.org/structure/6J5K] with bound inter-dimeric IF1.

Back to article page