Fig. 4: Overall structures of EV71/38-1-10A and EV71/38-3-11A complexes. | Nature Communications

Fig. 4: Overall structures of EV71/38-1-10A and EV71/38-3-11A complexes.

From: Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71

Fig. 4: Overall structures of EV71/38-1-10A and EV71/38-3-11A complexes.

a The structure of the EV71/38-1-10A complex viewed along an icosahedral twofold axis. The viral capsid proteins are shown as surface representations coloured in light blue, pale green and salmon for VP1, VP2 and VP3, respectively. For clarity, only the Vh and Vl domains of the Fab are shown as ribbons with Vh in magenta and Vl in cyan. One icosahedral asymmetric unit of the viron is outlined. b Close-up of 38-1-10A Fab binding around two threefolds. The colour scheme is as for a, but the virus is shown in grey. c Side view of b. Only one Fab is shown for clarity. d–f EV71/38-3-11A complex. The drawing, colour scheme and view direction of each panel are the same as that of a–c.

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