Fig. 1: Structure of CR3022 Fab bound to S in space-filling representation.
From: Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
Column on the left shows the native S, while that on the right shows S with bound CR3022. The top row shows a monomer of S1 without and with CR3022. The individual subunits are labelled and coloured according to the bar diagram at the bottom of the figure. The second row shows a full S1/S2 trimer in the same orientation as the top panel with one monomer coloured according to the top panel but the other S1 subunits are in grey. Where part of a coloured subunit is eclipsed by a grey subunit the surface is mottled; where there is a steric clash the surface of the coloured subunit is hatched. The third and fourth rows are orthogonal views to the top two rows with the trimer threefold axis vertical. The S2 chain associated with the coloured S1 chain is shown in red.
