Fig. 2: ctDNA is abundant in the CSF of paediatric patients with MB. | Nature Communications

Fig. 2: ctDNA is abundant in the CSF of paediatric patients with MB.

From: Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma

Fig. 2

a Heatmap representing the VAFs analysed by ddPCR from tumour DNA, and CSF and plasma ctDNA samples obtained before surgical resection for the 13 patients. Colour legend for mutant allelic frequencies (VAFs) is shown. VAFs values <10% are indicated. Not detected (ND). b Distribution of CSF ctDNA VAF. Outliers identified using ROUT method are highlighted with a grey circle and selected as High CSF ctDNA.

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