Fig. 4: Mechanistic studies. | Nature Communications

Fig. 4: Mechanistic studies.

From: Chiral phosphoric acid-catalyzed stereodivergent synthesis of trisubstituted allenes and computational mechanistic studies

Fig. 4

a Control experiments. b Initially proposed enol-type mode mechanism. c Comparison of the enol-type and Münchnone-type activation modes via calculation. d Energy profiles of Michael-Addition and proton transfer with CPA catalysts via DFT calculations. (The energy shown in kcal/mol, Ar = 3,5-dimethoxyphenyl).

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