Fig. 1: Benchmark test of MiSplice pipeline and sample set.
From: Discovery of driver non-coding splice-site-creating mutations in cancer
a Sensitivity curves derived by simulating various coverage levels and mutation distances plotted as a function of splice allele fraction (ratio of non-canonical junction reads over canonical junction reads). b Required junction read coverage to achieve sufficient power. c Sample data set processed by MiSplice pipeline. Source data are provided as a Source Data file.
