Fig. 3: Characterization of nc-SCMs from TCGA WGS data.
From: Discovery of driver non-coding splice-site-creating mutations in cancer
a Frequency distribution of the distance from mutations to splice sites and splicing score comparison between the reference and mutant primary splice sites for donors and acceptors. Blue and red colors represent introns and exons, respectively. b Splice score distribution of new exon splice sites. Red arrows represent negative changes in score, blue arrows represent positive changes in score, and dots represent little to no changes in score (change <0.5). Arrow length is proportional to the magnitude of the change. c Comparison of primary splice score before and after mutation, the activated mate score in new exons, and the score of 300 random control sites. Source data are provided as a Source Data file.
