Fig. 6: Experimental validation of nc-SCMs by the mini-gene splicing assay. | Nature Communications

Fig. 6: Experimental validation of nc-SCMs by the mini-gene splicing assay.

From: Discovery of driver non-coding splice-site-creating mutations in cancer

Fig. 6: Experimental validation of nc-SCMs by the mini-gene splicing assay.The alternative text for this image may have been generated using AI.

a Validation of non-coding splice-site-creating mutation candidates by the mini-gene splicing assay (“Methods”). All experiments were performed by three replicates and gave similar results (see Source Data file for the full scans). b Integrative Genomics Viewer (IGV) screenshot of four validated mutation-induced exon extension or shrinkage events. Red vertical lines indicate the mutation positions. Source data are provided as a Source Data file.

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