Fig. 3: Teosinte-maize CG differentially methylated regions and their associated functional features.
From: Evolutionary and functional genomics of DNA methylation in maize domestication and improvement
a Breakdown of hyper-DMRs (DMR hypermethylated in maize) and hypo-DMRs (DMR hypomethylated in maize) into genomic features and their overlaps with interactive anchors using data obtained from Li et al.33. Blue and red stars indicated DMRs that were significantly enriched at genomic features and interaction anchors (one-sided permutation test *P-value < 0.05, **P-value < 0.01). The numbers above the asterisks indicate the exact test P-values. b The distribution of the number of DMRs along the collapsed gene model. Below the figure shows a schematic gene model with three exons (black boxes). c Physical interactions (upper panel), colocalization with H3K27ac and H3K4me3 (middle panels), and STARR profiles (lower panels) around Zm00001d018036 gene in B73. STARR-seq data obtained from ref. 61 showed the transcriptional output (STARR-RNA) and DNA input (STARR-input) around this region. Blue curly lines indicate the interactive contacts between DMR and the candidate gene and gray curly lines indicate other interactive contacts around the region. Horizontal thick blue lines denote the interactive anchors. Red and gray boxes indicate the DMR and gene model, respectively. Source data underlying a, b are provided as a Source Data file.
