Fig. 3: Reconstruction of amino acid evolution at selected HAPMs.
From: Parallel evolution in the emergence of highly pathogenic avian influenza A viruses
Maximum clade credibility (MCC) trees showing the reconstruction of ancestral states for four illustrative HAPMs (a−d). Branches are coloured according to the inferred ancestral amino acid states (tip states not shown). Nodes representing the immediate LP ancestors and nodes from which the HP clusters directly descend are shown with circles. The posterior probabilities for a given amino acid state occurring at the specified node are indicated. The HP sequences (HP clusters) are highlighted in orange, whilst the immediate ancestral LP sequences are highlighted in grey. For details on sampling date, location, and host species, see Supplementary Figs. 5–8.
